METHOD OF PREVENTING CHRONIC TOXIC ARTERIAL HYPERTENSION AND CARDIOPATHY IN EXPERIMENTAL ANIMALS

摘要

FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, namely to toxicology and cardiology, and deals with prevention of chronic toxic arterial hypertension and cardiopathy in experimental animals. For this purpose 1 time per day lead acetate in dose 40 mg/kg and detoxicant are simultaneously introduced to animals intragastrically. As detoxicant introduced is preparation of melatonin melaxen in dose 10 mg/kg. ^ EFFECT: method ensures reduction of lead cytotoxicity due to membrane-protecting and antioxidant action of melatonin. ^ 1 tbl, 1 ex, 2 dwg