发明名称 |
MONOCLONAL ANTIBODY TO SPECIFIC MONKEY CD43 AND A HYBRIDOMA PRODUCING THE SAME |
摘要 |
PURPOSE: A high affinity monoclonal antibody anti-monkey CD43 antibody and a hybridoma producing the same are provided to recognize monkey-specific CD43 antigen with high affinity and to enhance T cell activation. CONSTITUTION: An anti-monkey CD43 monoclonal antibody is specific to CD43 antigen isolated from a monkey. The CD43 antibody contains a variable region of heavy chain having an amino acid of sequence number 1 and a variable region of light chain having an amino acid of sequence number 2. The monoclonal antibody is produced by a hydridoma(deposit number KCLRF-BP-00231). A composition for treating CD43+T cell-mediated or related diseases contains the CD43 antibody or a variant thereof.
|
申请公布号 |
KR20120081723(A) |
申请公布日期 |
2012.07.20 |
申请号 |
KR20110002997 |
申请日期 |
2011.01.12 |
申请人 |
SNU R&DB FOUNDATION |
发明人 |
PARK, CHUNG GYU;KIM, JUNG SIK;KIM, SANG JOON |
分类号 |
C07K16/18;A61K39/395;A61P35/00;C12N5/18 |
主分类号 |
C07K16/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|