发明名称 METHOD OF COMBINED TREATMENT OF NON-SMALL CELL LUNG CANCER OF II AND III STAGE
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention relates to medicine, namely to oncology, and deals with method of combined treatment of non-small cell lung cancer of II and III stage. Method includes 2 courses of neoadjuvant chemotherapy with application of carboplatin and further radical surgery. Neoadjuvant therapy is carried out by intravenous introduction of vinorelbine in dose 25 mg/ m2 on 1 and 8 days of cycle, on the second day, 20 hours after introduction of vinorelbine carboplatin is introduced intravenously by drop infusion in dose by AUG 6, interval between courses of chemotherapy constitutes 20 days. After that in post-operative period on 14 day additionally carried out is adjuvant chemotherapy in the same regimen, with number of course being 3-4. ^ EFFECT: invention ensures increased efficiency of treatment of non-small cell lung cancer of II and III stage due to reduction of complications and increase of patients' survival. ^ 2 ex
申请公布号 RU2455986(C1) 申请公布日期 2012.07.20
申请号 RU20110105847 申请日期 2011.02.16
申请人 UCHREZHDENIE ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT ONKOLOGII SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK (NII ONKOLOGII SO RAMN) 发明人 POLISHCHUK TAT'JANA VLADIMIROVNA;MILLER SERGEJ VIKTOROVICH;TUZIKOV SERGEJ ALEKSANDROVICH;GOL'DBERG VIKTOR EVGEN'EVICH;JUMOV EVGENIJ LEONIDOVICH
分类号 A61K31/282;A61K31/475;A61P35/00 主分类号 A61K31/282
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