发明名称 |
GYRASE AND TOPOISOMERASE IV INHIBITORS |
摘要 |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
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申请公布号 |
US2012184512(A1) |
申请公布日期 |
2012.07.19 |
申请号 |
US201213349789 |
申请日期 |
2012.01.13 |
申请人 |
LE TIRAN ARNAUD;GRILLOT ANNE-LAURE;CHARIFSON PAUL S.;BENNANI YOUSEF LAAFIRET;O'DOWD HARDWIN;PEROLA EMANUELE;VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
LE TIRAN ARNAUD;GRILLOT ANNE-LAURE;CHARIFSON PAUL S.;BENNANI YOUSEF LAAFIRET;O'DOWD HARDWIN;PEROLA EMANUELE |
分类号 |
A61K31/506;A01N43/54;A01N57/16;A01P1/00;A61K31/675;A61P31/04;C07D405/14;C07F9/09 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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