发明名称 GYRASE AND TOPOISOMERASE IV INHIBITORS
摘要 The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
申请公布号 US2012184512(A1) 申请公布日期 2012.07.19
申请号 US201213349789 申请日期 2012.01.13
申请人 LE TIRAN ARNAUD;GRILLOT ANNE-LAURE;CHARIFSON PAUL S.;BENNANI YOUSEF LAAFIRET;O'DOWD HARDWIN;PEROLA EMANUELE;VERTEX PHARMACEUTICALS INCORPORATED 发明人 LE TIRAN ARNAUD;GRILLOT ANNE-LAURE;CHARIFSON PAUL S.;BENNANI YOUSEF LAAFIRET;O'DOWD HARDWIN;PEROLA EMANUELE
分类号 A61K31/506;A01N43/54;A01N57/16;A01P1/00;A61K31/675;A61P31/04;C07D405/14;C07F9/09 主分类号 A61K31/506
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