发明名称 METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS
摘要 The invention relates to conjugates comprising a targeting moiety specific for the CXCR4 based on the polyphemusin-derived peptide and a therapeutic or imaging agent. The invention relates as well to the application of said conjugates for the therapy and diagnostics which require the specific targeting to CXCR4+ cells.
申请公布号 WO2012095527(A1) 申请公布日期 2012.07.19
申请号 WO2012EP50513 申请日期 2012.01.13
申请人 UNIVERSITAT AUTONOMA DE BARCELONA;INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANTPAU;CENTRO INVESTIGACION BIOMEDICA EN RED (CIBER BBN);VILLAVERDE CORRALES, ANTONIO;VAZQUEZ GOMEZ, ESTHER;CESPEDES NAVARRO, MARIA VIRTUDES;CASANOVA RIGAT, ISOLDA;FERRER MIRALLES, NEUS;MANGUES BAFALLUY, RAMON;UNZUETA ELORZA, UGUTZ 发明人 VILLAVERDE CORRALES, ANTONIO;VAZQUEZ GOMEZ, ESTHER;CESPEDES NAVARRO, MARIA VIRTUDES;CASANOVA RIGAT, ISOLDA;FERRER MIRALLES, NEUS;MANGUES BAFALLUY, RAMON;UNZUETA ELORZA, UGUTZ
分类号 A61K47/48;C07K14/435;C12N15/62 主分类号 A61K47/48
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