USE OF DERIVATIVES OF PENTAPHYRINE AS ANTIMICROBIAL AND DESINFECTANT AGENTS
摘要
<p>The invention relates to the use of 20-(4-carboxyphenyl)-2,13-dimethyl-3,12- diethyl-[22] pentaphyrine as antibacterial agent in photodynamic treatment. This expanded porphyrin derivatized in position 4 with a carboxyphenyl group proved very active after photo-oxidation both against S. aureus and E. hirae. Its high antibacterial activity and its low toxicity make this pentaphyrine particularly useful as antimicrobial agent both for photodynamic therapy against bacterial infections and in the disinfection of microbiologically contaminated liquids.</p>
申请公布号
WO2012035489(A9)
申请公布日期
2012.07.19
申请号
WO2011IB53992
申请日期
2011.09.13
申请人
UNIVERSITA' DEGLI STUDI DI UDINE;FEDELE, ROSALISA;COMUZZI, CLARA;ROSSI, GIADA;GOI, DANIELE