ORGANISMS WITH ALTERED STEROIDAL SAPONIN AND STEROIDAL ALKALOID LEVELS AND METHODS FOR PRODUCING SAME

摘要

The present invention relates to a key gene (designated GAME4) in the biosynthesis of steroidal saponins and steroidal (glyco) alkaloids and to means and methods for altering its expression. The invention further provides genetically modified organisms having altered levels of steroidal saponins and/or steroidal alkaloids compared to unmodified organisms. The metabolites produced by the genetically modified organisms may be further used in the pharmaceutics industry.