The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti¬ bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.
申请公布号
CA2824516(A1)
申请公布日期
2012.07.19
申请号
CA20122824516
申请日期
2012.01.13
申请人
VERTEX PHARMACEUTICALS INCORPORATED
发明人
LE TIRAN, ARNAUD;GRILLOT, ANNE-LAURE;CHARIFSON, PAUL, S.;BENNANI, YOUSSEF LAAFIRET;O'DOWD, HARDWIN;PEROLA, EMANUELE