| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a widely applicable and highly effective therapeutic agent by improving an antisense oligonucleotide to a splicing enhancer sequence (SES) present in exon 19, 41, 45, 46, 44, 50, 55, 51 or 53 of a dystrophin gene. <P>SOLUTION: There are provided oligonucleotides having a base sequence complementary to a specific nucleotide of a dystrophin cDNA (Gene Bank accession No. NM_004006.1), and a muscular dystrophy therapeutic agent containing the same. <P>COPYRIGHT: (C)2012,JPO&INPIT |
