发明名称 MOLECULES CAPABLE OF INDUCING CELL DEATH BY TARGETING THE MITOCHONDRIA AND APPLICATIONS THEREOF
摘要 The invention relates to the use of derivatives of the membrane insertion regions of proteins of the Bcl-2 family to induce cell death by targeting the mitochondria, characterised in that said derivatives are peptides belonging to regions α5 and/or α6 of the Bax protein or equivalent regions found in the other proteins of the Bcl-2 family.
申请公布号 EP2475680(A1) 申请公布日期 2012.07.18
申请号 EP20100760064 申请日期 2010.09.08
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.);UNIVERSITE CLAUDE BERNARD LYON 1 发明人 AOUACHERIA, ABDEL
分类号 C07K14/47;A23L33/00;A61K38/17 主分类号 C07K14/47
代理机构 代理人
主权项
地址