发明名称 |
MOLECULES CAPABLE OF INDUCING CELL DEATH BY TARGETING THE MITOCHONDRIA AND APPLICATIONS THEREOF |
摘要 |
The invention relates to the use of derivatives of the membrane insertion regions of proteins of the Bcl-2 family to induce cell death by targeting the mitochondria, characterised in that said derivatives are peptides belonging to regions α5 and/or α6 of the Bax protein or equivalent regions found in the other proteins of the Bcl-2 family. |
申请公布号 |
EP2475680(A1) |
申请公布日期 |
2012.07.18 |
申请号 |
EP20100760064 |
申请日期 |
2010.09.08 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.);UNIVERSITE CLAUDE BERNARD LYON 1 |
发明人 |
AOUACHERIA, ABDEL |
分类号 |
C07K14/47;A23L33/00;A61K38/17 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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