发明名称 HORMONE COMBINATION FOR ALLEVIATION OF MENSTRUAL CYCLE DEPENDENT MOOD FLUCTUATIONS
摘要 <p>Use of a hormone combination of at least an estrogen from ethinyl estradiol (I) and estradiol (II) and at least metabolites of chlormadinone acetate e.g. 3alpha -hydroxy-6-chloro-17alpha -acetoxy-4,6-pregnadiene-20-one (3alpha -hydroxy-chlormadione acetate), optionally mixed with chlormadione acetate as gestagen components, for the production of a medicament for the reduction of menstruation cycle-dependent mood changes and optionally for hormonal contraception in women. Use of a hormone combination of at least an estrogen from ethinyl estradiol (I) and estradiol (II) as estrogen components and at least metabolites of chlormadinone acetate from 3alpha -hydroxy-6-chloro-17alpha -acetoxy-4,6-pregnadiene-20-one (3alpha -hydroxy-chlormadione acetate), 3beta -hydroxy-6-chloro-17alpha -acetoxy-4,6-pregnadiene-20-one (3beta -hydroxy-chlormadione acetate), 3alpha -hydroxy-6-chloro-17alpha -acetoxy-5beta -pregnane-20-one and 3alpha -hydroxy 17alpha -acetoxy-5beta -pregnane-20-one, optionally mixed with chlormadione acetate as gestagen components, for the production of a medicament for the reduction of menstruation cycle-dependent mood changes and optionally for hormonal contraception in women. ACTIVITY : Contraceptive; Neuroprotective. MECHANISM OF ACTION : None given.</p>
申请公布号 EP1978969(B1) 申请公布日期 2012.07.18
申请号 EP20070702961 申请日期 2007.01.23
申请人 RICHTER GEDEON NYRT. 发明人 SCHRAMM, GEORG;KNEIP, CHRISTA
分类号 A61K31/565;A61K31/57 主分类号 A61K31/565
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