发明名称 |
METHOD FOR INHIBITING SCAVENGER RECEPTOR-A AND INCREASING IMMUNE RESPONSE TO ANTIGENS |
摘要 |
Provided is a method for enhancing an immune response to a desired antigen in an individual. The method is performed by administering to the individual an agent capable of inhibiting class A macrophage scavenger receptor (SR-A) and optionally administering the desired antigen. Also provided is a method for enhancing an immune response to an antigen by administering to an individual a composition containing antigen presenting cells that are characterized by specifically inhibited SR-A. Substantially purified populations of mammalian dendritic cells characterized by specifically inhibited SR-A are also provided. |
申请公布号 |
EP2147011(A4) |
申请公布日期 |
2012.07.18 |
申请号 |
EP20080745977 |
申请日期 |
2008.04.16 |
申请人 |
HEALTH RESEARCH, INC. |
发明人 |
WANG, XIANG-YANG;SUBJECK, JOHN |
分类号 |
C07H21/02;A01N43/04;A61K31/70;C07H21/04;C12N15/113 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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