| 发明名称 |
Ketol-acid reductoisomerase using NADH |
| 摘要 |
Methods for the evolution of NADPH binding ketol-acid reductoisomerase enzymes to acquire NADH binding functionality are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from Pseudomonas that have undergone co-factor switching to bind NADH are described.
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| 申请公布号 |
US8222017(B2) |
申请公布日期 |
2012.07.17 |
| 申请号 |
US201113296969 |
申请日期 |
2011.11.15 |
| 申请人 |
LI YOUGEN;LIAO DER-ING;NELSON MARK J.;OKEEFE DANIEL P.;TOMB JEAN-FRANCOIS;BUTAMAX(TM) ADVANCED BIOFUELS LLC |
发明人 |
LI YOUGEN;LIAO DER-ING;NELSON MARK J.;OKEEFE DANIEL P.;TOMB JEAN-FRANCOIS |
| 分类号 |
C12N9/02;C07H21/04;C12N15/00;C12P21/04;C12P21/06 |
主分类号 |
C12N9/02 |
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