| 发明名称 |
Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy |
| 摘要 |
The present invention relates to compositions and methods for delivery of siRNA to specific cells or tissue. More particularly, the present invention relates to compositions and methods for cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer. |
| 申请公布号 |
US8222226(B2) |
申请公布日期 |
2012.07.17 |
| 申请号 |
US201113108136 |
申请日期 |
2011.05.16 |
| 申请人 |
ROSSI JOHN J.;ZHOU JIEHUA;CITY OF HOPE |
发明人 |
ROSSI JOHN J.;ZHOU JIEHUA |
| 分类号 |
C07H21/04;C12N15/113;C12N15/115 |
主分类号 |
C07H21/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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