发明名称 MODULATORS OF IL-12 AND/OR IL-23 FOR THE PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE
摘要 The invention provides antibody against p40, IL-12 or IL-23 for the prevention or treatment of Alzheimer's disease. It further provides ligands to the pair of interleukin 12 or 23 and its specific receptor, specifically an antibody, an antibody fragment, an antibody-like- molecule, for the prevention or treatment of Alzheimer's disease. Similarly, siRNA, antisense or transcription factor modulators of gene expression of p19, p35, p40, IL-12R- ß1, IL-12R-ß2, and/or IL-23R for the prevention or treatment of Alzheimer's disease are provided.
申请公布号 WO2012093127(A2) 申请公布日期 2012.07.12
申请号 WO2012EP50066 申请日期 2012.01.04
申请人 UNIVERSITAET ZUERICH;CHARITE UNIVERSITAETSMEDIZIN BERLIN;BECHER, BURKHARD;HEPPNER, FRANK 发明人 BECHER, BURKHARD;HEPPNER, FRANK
分类号 C07K16/18;A61P25/28 主分类号 C07K16/18
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