摘要 |
<P>PROBLEM TO BE SOLVED: To provide an endogenous humanin receptor agonist having a stronger activity for inhibiting the functional disorder or death of nerve cells than that of humanin. <P>SOLUTION: The pharmaceutical composition includes, as an active ingredient, a peptide having an amino acid sequence comprising formula (I): TGKNLSEAGLRKLI(S or G)EVDSDGD(each letter shows one amino acid) (I) and having an activity for inhibiting the functional disorder or death of nerve cells, a polypeptide having the amino acid sequence comprising formula (I) and having the activity for inhibiting the functional disorder or death of the nerve cells, or the like. <P>COPYRIGHT: (C)2012,JPO&INPIT |