发明名称 TIE2 ACTIVATOR, VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, ANTI-ANGIOGENIC AGENT, AGENT FOR MATURING BLOOD VESSELS, AGENT FOR NORMALIZING BLOOD VESSELS, AGENT FOR STABILIZING BLOOD VESSELS, AND PHARMACEUTICAL COMPOSITION
摘要 <P>PROBLEM TO BE SOLVED: To provide a Tie2 activator, a vascular endothelial growth factor (VEGF) inhibitor, an anti-angiogenic agent, an agent for maturing blood vessels, an agent for normalizing blood vessels and an agent for stabilizing blood vessels, which are highly safe and respectively have superior Tie2 activating effect, vascular endothelial growth factor (VEGF) inhibitory effect, anti-angiogenic effect, blood vessel maturing effect, blood vessel normalizing effect and blood vessel stabilizing effect; and to provide a pharmaceutical composition. <P>SOLUTION: The Tie2 activator, the vascular endothelial growth factor (VEGF) inhibitor, the anti-angiogenic agent, the agent for maturing blood vessels, the agent for normalizing blood vessels and the agent for stabilizing blood vessels each containing an extract of hawthorn as an active ingredient, and the pharmaceutical composition are provided. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012131766(A) 申请公布日期 2012.07.12
申请号 JP20110105696 申请日期 2011.05.10
申请人 MARUZEN PHARMACEUT CO LTD 发明人 KISO AKINORI;OTO NOBUAKI
分类号 A61K36/73;A61P9/14;A61P35/00;A61P43/00 主分类号 A61K36/73
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