| 发明名称 |
NOVEL GLUCOKINASE ACTIVATORS AND PROCESSES FOR THE PREPARATION THEREOF |
| 摘要 |
The present invention provides an amide derivative having a stilbene or 1,2-diphenylethane moiety within the molecule thereof, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The amide derivative of the present invention activates glucokinase remarkably, and therefore they can be usefully applied for treating glucokinase-mediated diseases, such as hyperglycemia and diabetes. |
| 申请公布号 |
US2012178765(A1) |
申请公布日期 |
2012.07.12 |
| 申请号 |
US201013497219 |
申请日期 |
2010.09.17 |
| 申请人 |
YI WON-HUI;HAN TAE-DONG;LEE KOO-YEON;KIM YOUNG-HWAN;JUNG EUN-HYE;LEE DONG-HOON;PARK YOO-HOI;MIN KYUNG-NAN;KIM JAE-GYU;LEE BYUNG-KYU;YUHAN CORPORATION |
发明人 |
YI WON-HUI;HAN TAE-DONG;LEE KOO-YEON;KIM YOUNG-HWAN;JUNG EUN-HYE;LEE DONG-HOON;PARK YOO-HOI;MIN KYUNG-NAN;KIM JAE-GYU;LEE BYUNG-KYU |
| 分类号 |
A61K31/4965;A61K31/415;A61K31/426;A61K31/455;A61P3/10;C07D213/80;C07D231/40;C07D241/20;C07D277/46 |
主分类号 |
A61K31/4965 |
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