发明名称 |
THE EMBODIMENTS OF THE INVENTION FOR WHICH AN EXCLUSIVE PROPERTY OR PRIVALEGE IS CLAIMED ARE DEFINED AS FOLLOWS |
摘要 |
Provided herein are methods and recombinant expression systems for the production of recombinant glycoproteins that have increased sialic acid content and contain predominantly alpha2-6 sialic acid linkages. Also provided herein are recombinant glycoproteins that have an increased in vivo circulatory half-life. One potential application of the glycoproteins described herein is for the treatment and prophylaxis of poisoning by neurotoxins. |
申请公布号 |
CA2817765(A1) |
申请公布日期 |
2012.07.12 |
申请号 |
CA20122817765 |
申请日期 |
2012.01.06 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
BETENBAUGH, MICHAEL J. |
分类号 |
C12N5/10;A61K8/60;C07K9/00;C12N15/12;C12N15/52 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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