| 发明名称 |
Antibodies That Specifically Bind to A Beta Oligomers and Use Thereof |
| 摘要 |
The present inventors successfully produced monoclonal antibodies that are specific to only soluble A beta oligomers, but do not recognize soluble A beta monomers, which are physiological molecules. It was demonstrated that the antibodies are useful as diagnostic/therapeutic monoclonal antibodies for Alzheimer's disease. |
| 申请公布号 |
US2012177664(A1) |
申请公布日期 |
2012.07.12 |
| 申请号 |
US201013389229 |
申请日期 |
2010.08.05 |
| 申请人 |
YOKOSEKI TATSUKI;OKAMOTO YASUHIDE;UMEDA MAKOTO;TAKAMATSU NAOFUMI;ITO TOSHIYUKI;IMAI YUKIHO;FUJII SHINOBU;IMMUNAS PHARMA, INC. |
发明人 |
YOKOSEKI TATSUKI;OKAMOTO YASUHIDE;UMEDA MAKOTO;TAKAMATSU NAOFUMI;ITO TOSHIYUKI;IMAI YUKIHO;FUJII SHINOBU |
| 分类号 |
A61K39/395;A61P25/00;A61P25/28;C07K16/18;G01N33/566 |
主分类号 |
A61K39/395 |
| 代理机构 |
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