发明名称 |
ANTI-HUMAN IL-21 MONOCLONAL ANTIBODIES |
摘要 |
Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinant IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeutic treatment of autoimmune and inflammatory diseases, particularly diseases mediated by T follicular helper cells, B cells, TH cells or TH17 cells.
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申请公布号 |
US2012177655(A1) |
申请公布日期 |
2012.07.12 |
申请号 |
US201213348366 |
申请日期 |
2012.01.11 |
申请人 |
JASPERS STEPHEN R.;RIXON MARK W.;DILLON STACEY R.;RAMSDELL FREDERICK J.;KREJSA CECILE M.;YI EUGENE C.;ZYMOGENETICS, INC. |
发明人 |
JASPERS STEPHEN R.;RIXON MARK W.;DILLON STACEY R.;RAMSDELL FREDERICK J.;KREJSA CECILE M.;YI EUGENE C. |
分类号 |
A61K39/395;A61P1/00;A61P3/10;A61P19/02;A61P25/00;A61P29/00;A61P37/00;C07K16/24;C12N5/16 |
主分类号 |
A61K39/395 |
代理机构 |
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主权项 |
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地址 |
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