发明名称 |
ANTIGEN-BINDING PROTEINS |
摘要 |
The invention relates to combinations of HGF antagonists with VEGF antagonists, and provides antigen-binding proteins which bind to HGF comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding protein has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof. |
申请公布号 |
US2012177651(A1) |
申请公布日期 |
2012.07.12 |
申请号 |
US201013322207 |
申请日期 |
2010.05.26 |
申请人 |
CLARKE NEIL JAMES;FORD SUSANNAH KAREN;HAMBLIN PAUL ANDREW;MARTIN STEPHEN |
发明人 |
CLARKE NEIL JAMES;FORD SUSANNAH KAREN;HAMBLIN PAUL ANDREW;MARTIN STEPHEN |
分类号 |
A61K39/395;C07K16/18;C12N1/21;C12N5/10;C12P21/06 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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