发明名称 |
Novel Screening Strategies for the Identification of Binders |
摘要 |
The present invention discloses novel screening strategies for the identification of binders that target the active site of enzymatic antigens. The present invention also discloses antigen-binding moieties which bind to the NS2B-NS3 Proteinase of West Nile Virus, in particular binders which bind to the active site, thereby inhibiting the enzymatic activity of the proteinase. The antigen-binding moieties of the present invention have numerous therapeutic and diagnostic applications. |
申请公布号 |
US2012178909(A1) |
申请公布日期 |
2012.07.12 |
申请号 |
US201013379680 |
申请日期 |
2010.08.06 |
申请人 |
FRISCH CHRISTIAN;KNAPPIK ACHIM;STRONGIN ALEX Y.;SHIRYAEV SERGEY A.;MORPHOSYS AG |
发明人 |
FRISCH CHRISTIAN;KNAPPIK ACHIM;STRONGIN ALEX Y.;SHIRYAEV SERGEY A. |
分类号 |
C40B30/04;C07K1/14;C07K16/00 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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