发明名称 |
MATERIALS PRESENTING NOTCH SIGNALING MOLECULES TO CONTROL CELL BEHAVIOR |
摘要 |
The invention provides a solution to the problem of delivering molecules in a physiologically relevant manner to direct cell fate. For example, a Notch ligand molecule is presented in a micro-environment that mimics the environment encountered in vivo. Accordingly, the invention features a cell delivery vehicle comprising a biocompatible hydrogel or polymer and a composition that binds to a Notch receptor and methods of directing cell fate, e.g., stem cell differentiation, using such compositions. |
申请公布号 |
WO2012064697(A3) |
申请公布日期 |
2012.07.12 |
申请号 |
WO2011US59710 |
申请日期 |
2011.11.08 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;CAO, LAN;BOUHARDIR, KAMAL H.;MOONEY, DAVID J. |
发明人 |
CAO, LAN;BOUHARDIR, KAMAL H.;MOONEY, DAVID J. |
分类号 |
A61K47/48;A61K31/4015;A61K31/7052;A61K31/7056;A61K35/12;A61K38/18;A61K38/28 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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