NOVEL ANTISENSE OLIGONUCLEOTIDES

摘要

A purified and isolated antisense molecule capable of binding to a selected target site to induce exon skipping and/or translation blocking in the granulocyte macrophage colony-stimulating factor gene (GM-CSF) selected from the antisense molecules of SEQ ID NO: 1 to 17. Methods of treating conditions associated with abnormal levels of GM- CSF such as asthma, rheumatoid arthritis, acute myeloid leukaemia are also disclosed.