| 发明名称 |
ENHANCED PROTEIN PURIFICATION THROUGH A MODIFIED PROTEIN A ELUTION |
| 摘要 |
The present invention provides methods for purifying a polypeptide comprising a CH2/CH3 region, comprising binding the polypeptide to Protein A and eluting with a pH gradient starting at a low pH. |
| 申请公布号 |
EP2473617(A1) |
申请公布日期 |
2012.07.11 |
| 申请号 |
EP20100814394 |
申请日期 |
2010.09.01 |
| 申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
BROWN, ARICK;DOWD, CHRISTOPHER, J.;RADHAMOHAN, ASHA, NANDINI |
| 分类号 |
C12P21/00;C07K1/22;G01N33/53 |
主分类号 |
C12P21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
