发明名称 |
SDF-1 DELIVERY FOR TREATING ISCHEMIC TISSUE |
摘要 |
A method of treating a cardiomyopathy in a subject includes administering directly to or expressing locally in a weakened, ischemic, and/or peri-infarct region of myocardial tissue of the subject an amount of SDF-1 effective to cause functional improvement in at least one of the following parameters: left ventricular volume, left ventricular area, left ventricular dimension, cardiac function, 6-minute walk test, or New York Heart Association (NYHA) functional classification. |
申请公布号 |
EP2473196(A2) |
申请公布日期 |
2012.07.11 |
申请号 |
EP20100812718 |
申请日期 |
2010.08.30 |
申请人 |
THE CLEVELAND CLINIC FOUNDATION |
发明人 |
PENN, MARC, S.;ARAS, RAHUL;PASTORE, JOSEPH;MILLER, TIMOTHY, J. |
分类号 |
C07K14/52;A61K9/00;A61K31/711;A61K38/00 |
主分类号 |
C07K14/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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