发明名称 METHOD AND APPARATUS FOR PREDICTING PROPERTIES OF GRANULATED MATERIALS AND DOSAGE FORMS MADE THEREFROM
摘要 A method and system for estimating, predicting, and/or controlling a granulation process are disclosed. The method may account for changes in input water amount, how material responds to the water amount, batch size, power input, and particle size, specific surface area, or dynamic cohesion of the materials being granulated. The method may also account for an impeller load, relative impeller efficiency, and water content. The method may measure point where material being granulated is responding to the water addition. The method may predict tap density of the granules exiting a mill downstream of granulation, after a drying process. The method may predict tablet dissolution. The system may include a controller having a computer executable program embodied in a computer readable medium and configured to perform one or more steps of the method. The system may also control various processing equipment in response to estimates and/or predictions.
申请公布号 EP2238283(A4) 申请公布日期 2012.07.11
申请号 EP20090705991 申请日期 2009.01.30
申请人 GLAXOSMITHKLINE LLC 发明人 CLANCY, DONALD, JAMES
分类号 D04H3/16;B01J2/10 主分类号 D04H3/16
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