发明名称 METHOD OF DIAGNOSING TUMOUR PROCESS DISSEMINATION IN PATIENTS WITH NON-SMALL-CELL LUNG CARCINOMA
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to medicine, radio-, radionuclide diagnostics in oncology. Performed is simultaneous two-isotope emission computed tomography, with two tumour-tropic radiopharmaceuticals (RP), which have different mechanism of accumulation in tumour: 48-72 hours after intravenous introduction to patient of 150-200 MBq solution of 67 Ga-citrate and 10-15 minutes after intravenous introduction to patient of 370-740 MBq solution of 99 mTc-technetril. Distribution of 67 Ga on three peaks: 93 keV, 184 keV, 300 keV and 99 mTc-technetril - on peak 140 keV with 10% window is registered. If there are foci of pathologic hyperfixation in lungs and/or regional lymph nodes of at least one of the two used tumour-tropic RP, dissemination of tumour process is determined. ^ EFFECT: method ensures essential increase of accuracy of determination of non-small-cell lung carcinoma dissemination irrespective on its histological structure and functional state of primary tumour, spread of affection of regional lymph nodes of various types, reduction of examination time. ^ 2 dwg, 2 ex
申请公布号 RU2454931(C1) 申请公布日期 2012.07.10
申请号 RU20110108103 申请日期 2011.03.02
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT ONKOLOGII IMENI N.N. PETROVA" MINISTERSTVA ZDRAVOOKHRANENIJAI SOTSIAL'NOGO RAZVITIJA ROSSIJSKOJ FEDERATSII 发明人 KANAEV SERGEJ VASIL'EVICH;NOVIKOV SERGEJ NIKOLAEVICH;GIRSHOVICH MIKHAIL MARKOVICH;LEVCHENKO EVGENIJ VLADIMIROVICH;BEJNUSOV DMITRIJ SERGEEVICH
分类号 A61B5/055;A61K49/06 主分类号 A61B5/055
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