发明名称 Process for producing cyclic N-hydroxy imide compounds
摘要 A cyclic polycarboxylic acid anhydride, a polycarboxylic acid, or a mixture of them is allowed to react with hydroxylamine or a salt thereof in an organic solvent under dewatering conditions to yield a corresponding cyclic N-hydroxyimide compound. The cyclic polycarboxylic acid anhydride can be, for example, succinic anhydride or glutaric anhydride. The polycarboxylic acid can be, for example, succinic acid, glutaric acid, or adipic acid. In this process, the reaction is preferably carried out using an organic solvent capable of undergoing azeotropy with water as all or part of a reaction solvent while removing water from the reaction system by azeotropy with the organic solvent. This process produces a cyclic N-hydroxyimide compound in a good yield from any of a cyclic polycarboxylic acid anhydride and a polycarboxylic acid.
申请公布号 US8217182(B2) 申请公布日期 2012.07.10
申请号 US20090510393 申请日期 2009.07.28
申请人 KAJIKAWA YASUTERU;DAICEL CHEMICAL INDUSTRIES, LTD. 发明人 KAJIKAWA YASUTERU
分类号 A61K31/395;A61K31/35;C07D201/00;C07D207/46;C07D209/48;C07D211/94;C07D223/10;C07D307/02;C07D309/02;C07D309/32;C07D487/04 主分类号 A61K31/395
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