发明名称 MANIPULATION OF THE RATE OF GASTROINTESTINAL TRANSIT BY MODULATING INTESTINAL METHANE CONCENTRATION
摘要 <p>Disclosed is a method of manipulating the rate of gastrointestinal transit in a mammalian subject. Also disclosed is the use, in the manufacture of a medicamens for the treatment of constipation, of a selective inhibitor of methanogensis, a methanogen-displacing probiotic agent, or a prebiotic agent that inhibits the growth of methanogenic bacteria or promotes the growth of competing non-methanogenic intestinal flora. Alternatively, in accordance with the invention, is disclosed the use in the manufacture of a medicament for the treatment of diarrhea, of methane, or a methane precursor, a methanogenic or other methane-enhancing probiotic agent, or a methanogenesis-enhancing prebiotic agent.</p>
申请公布号 CA2486585(C) 申请公布日期 2012.07.10
申请号 CA20032486585 申请日期 2003.05.20
申请人 CEDARS-SINAI MEDICAL CENTER 发明人 LIN, HENRY C.;PIMENTEL, MARK
分类号 A61K35/74;A61K45/00;A61K31/351;A61K31/74;A61P1/00;A61P1/10;A61P1/12;C12N1/00;C12N1/12;C12N1/20 主分类号 A61K35/74
代理机构 代理人
主权项
地址