5-AMINO- 4-HYDROXYPENTOYL AMIDES.

摘要

HIV inhibitors of formula (I) wherein R1 is halo, C1-4alkoxy, trifluoromethoxy; R2is a group of formula (A); R3is a group of formula (B); R4is a group of formula (C); n is 0 or 1; A is CH or N; R5and R6are hydrogen, C1-4alkyl, halo; R7and R8are C1-4alkyl or C1-4alkoxyC1-4alkyl; R9is C1-4alkyl, cyclopropyl, trifluoromethyl, C1-4alkoxy, or dimethylamino; R10is hydrogen, C1-4alkyl, cyclopropyl, trifluoromethyl, C1-4alkoxy, or dimethylamino; pharmaceutically acceptable addition salts and solvates thereof; pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds.