Antimicrobial and anti-inflammatory action pharmaceutical composition for parenteral administration, process of producing the same

摘要

This invention is related to pharmacology, medicine, veterinary science and pharmaceutical industry. It particularly belongs to original composite antimicrobial preparations for parenteral administration production process, which poses a higher therapeutic efficiency in case of grave infection and inflammatory diseases. Proposed pharmaceutical compositions active agents are fosfomicin and finely dispersed nanostructured silica dioxide. The mentioned pharmaceutical composition production process includes mixing fosfomicin with finely dispersed nanostructured silica dioxide. Its' main difference is that the mentioned substances mixture with weight ratio from 10:1 to 75:1 respectively is being exposed to mechanical processing by impact and abrasive actions until fine powder fraction weight proportion increase (< 5 micron) and becomes not less than 25%. The received mixture is used for injection preparation.