发明名称 |
Methods of Inducing Tissue Regeneration |
摘要 |
Methods are provided for producing cells within a lineage (lineage restricted cells) from post-mitotic differentiated cells of the same lineage ex vivo and in vivo, and for treating a subject in need of tissue regeneration therapy by employing these lineage-restricted cells. In addition, the production of lineage restricted cells from postmitotic tissues derived from patients with diseases allows for a characterization of pathways that have gone awry in these diseases and for screening of drugs that will ameliorate or correct the defects as a means of novel drug discovery. Also provided are kits for performing these methods. |
申请公布号 |
US2012171174(A1) |
申请公布日期 |
2012.07.05 |
申请号 |
US201013394798 |
申请日期 |
2010.11.17 |
申请人 |
BLAU HELEN M.;PAJCINI KOSTANDIN;POMERANTZ JASON |
发明人 |
BLAU HELEN M.;PAJCINI KOSTANDIN;POMERANTZ JASON |
分类号 |
A61K35/12;C12N5/071;C12Q1/02;C12Q1/68;G01N21/64;G01N33/53 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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