发明名称 Method for Modulating Responsiveness to Steroids
摘要 A method for enhancing steroid efficacy in a steroid refractory patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment comprises administering an oligonucleotide having the sequence formula (SEQ. ID. No. 18) 5′-Xm-TTCGT-Yn-3′ in an effective amount to said patient and wherein X is A, T, C or G, Y is A, T, C or G, m=0-7, n=0-7 and wherein at least one CG dinucleotide is unmethylated.
申请公布号 US2012172420(A1) 申请公布日期 2012.07.05
申请号 US201213410121 申请日期 2012.03.01
申请人 SPIIK ANN-KRISTIN;LOEFBERG ROBERT;BANDHOLTZ LISA CHARLOTTA;STEIN OLIVER VON;ZARGARI AREZOU 发明人 SPIIK ANN-KRISTIN;LOEFBERG ROBERT;BANDHOLTZ LISA CHARLOTTA;STEIN OLIVER VON;ZARGARI AREZOU
分类号 A61K31/7088;A61K31/7115;A61K31/7125;A61P29/00 主分类号 A61K31/7088
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