| 发明名称 |
PEPTIDOMIMETIC MACROCYCLES |
| 摘要 |
The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provides methods of identifying and making such improved polypeptides. |
| 申请公布号 |
US2012172311(A1) |
申请公布日期 |
2012.07.05 |
| 申请号 |
US201213366113 |
申请日期 |
2012.02.03 |
| 申请人 |
NASH HUW M.;ANNIS DAVID ALLEN;KAPELLER-LIBERMANN ROSANA;SAWYER TOMI K.;KAWAHATA NORIYUKI;AILERON THERAPEUTICS, INC. |
发明人 |
NASH HUW M.;ANNIS DAVID ALLEN;KAPELLER-LIBERMANN ROSANA;SAWYER TOMI K.;KAWAHATA NORIYUKI |
| 分类号 |
A61K38/02;A61P35/00;C07K2/00;G06F19/00 |
主分类号 |
A61K38/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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