发明名称 IMMUNOGENIC AND THERAPEUTIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES
摘要 <P>PROBLEM TO BE SOLVED: To provide a group A Streptcoccal (GAS) antigen useful for obtaining immunity against supprative infection. <P>SOLUTION: This composition contains at least one active factor selected from the group consisting of (a) a surface-exposed GAS antigen by at least one amino acid shorter than a GAS protein, including a surface-exposed domain of the GAS protein, where the GAS protein is selected from the group consisting of a specific GAS protein, an M protein, SagA, Sfb1 and Shp, (b) a nucleic acid molecule encoding the GAS antigen and (C) an antibody binding specifically to the GAS antigen. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012126742(A) 申请公布日期 2012.07.05
申请号 JP20120071927 申请日期 2012.03.27
申请人 NOVARTIS VACCINES & DIAGNOSTICS SRL 发明人 BENSI GIULIANO;GRANDI GUIDO;NORAIS NATHALIE;ORTEGA MANUEL RODRIGUEZ J
分类号 A61K31/7088;A61K39/09;A61K39/395;A61K47/42;A61K47/48;A61K48/00;A61P31/04;C07K14/195;C07K16/12;C12N15/09 主分类号 A61K31/7088
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