发明名称 |
METHODS AND KITS FOR LINKING POLYMORPHIC SEQUENCES TO EXPANDED REPEAT MUTATIONS |
摘要 |
Methods and kits are provided for determining which single nucleotide polymorphism (“SNP”) variant of an allele of a heterozygous patient is on the same allele as a disease-causing mutation. Also, provided are kits for multi-SNP diagnosis and treatment, targeting combinations of SNPs having greater joint prevalence of heterozygosity in Huntington's population than individual SNPs considered individually.
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申请公布号 |
US2012172409(A1) |
申请公布日期 |
2012.07.05 |
申请号 |
US20080601292 |
申请日期 |
2008.05.22 |
申请人 |
VAN BILSEN PAUL;BURRIGHT ERIC N.;KAEMMERER WILLIAM F.;JASPERS LEONIE;LOMBARDI MARIA STELLA;MEDTRONIC, INC. |
发明人 |
VAN BILSEN PAUL;BURRIGHT ERIC N.;KAEMMERER WILLIAM F.;JASPERS LEONIE;LOMBARDI MARIA STELLA |
分类号 |
A61K31/713;A61P25/00;A61P25/14;C12Q1/68 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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