METHOD FOR TRIGGERING DEPENDENT SPECTRA FOR DATA ACQUISITION
摘要
Methods and systems are provided for triggering an information dependent mass spectrometry scan in real time. A mass spectrometry scan of a separating sample mixture is performed by a mass spectrometer at each time interval of a time period. The mass spectrometer receives the separating sample mixture from a separation device. It is determined at a certain time interval that a received mass spectrometry scan at the time interval and one or more preceding received mass spectrometry scans include two or more time-varying ion signals that represent two or more fragment ion transitions of a known compound. If a characteristic of the two or more time-varying ion signals meets a selection criterion, the mass spectrometer is instructed to perform a dependent mass spectrometry scan of the separating sample mixture for a precursor ion of the known compound at the time interval.
申请公布号
WO2012090046(A1)
申请公布日期
2012.07.05
申请号
WO2011IB03107
申请日期
2011.12.22
申请人
DH TECHNOLOGIES DEVELOPMENT PTE. LTD.;COX, DAVID, M.;TATE, STEPHEN, A.;GLUECKMANN, MATTHIAS