| 摘要 |
<p>Disclosed is an aromatic alkyne derivative as a protein kinase inhibitor. The compound is a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R4, ring A, ring B, L, m, n, p or q are as specifically defined in the specification. In addition, also disclosed is a drug with the compound or a salt thereof as an active ingredient, which is useful in treatment of proliferative diseases such as cancer and inflammatory diseases, and especially Bcr-Abl tyrosine kinase related diseases.</p> |
