发明名称 |
METHOD FOR CULTURE OF HEPATOCYTES |
摘要 |
A method for culturing hepatocytes, wherein hepatocytes embedded in an extracellular matrix is placed on a gas-permeable membrane and the hepatocytes are cultured while being supplied with oxygen from the gas-permeable membrane side. By this, the polarity in the hepatocytes can be induced and a bile canaliculus can be formed in a short period of time. Further, the formed polarity can be maintained for a longer period. |
申请公布号 |
EP2471908(A1) |
申请公布日期 |
2012.07.04 |
申请号 |
EP20100811643 |
申请日期 |
2010.07.28 |
申请人 |
THE UNIVERSITY OF TOKYO;MITSUBISHI CHEMICAL MEDIENCE CORPORATION |
发明人 |
MATSUI, HITOSHI;SAKAI, YASUYUKI;FUJII, TERUO;TAKEUCHI, SHOJI;TSUDA, YUKIKO |
分类号 |
C12N5/071;C12M1/34;C12Q1/02 |
主分类号 |
C12N5/071 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|