发明名称 |
METHODS OF TREATING FIBROSING DISEASES BY INDUCTION OF IMMUNE TOLERANCE |
摘要 |
The present invention has demonstrated for the first time that orally administered type I collagen (CI) induced tolerance to CI in patients suffering from systemic sclerosis (SSc) and ameliorated clinical manifestations of the disease. Accordingly, the present invention provides methods of treating a fibrosing disease by oral administration of a tissue protein, for example, collagen, derived from the tissue undergoing fibrosis. |
申请公布号 |
EP1965813(A4) |
申请公布日期 |
2012.07.04 |
申请号 |
EP20060837669 |
申请日期 |
2006.11.16 |
申请人 |
THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION |
发明人 |
POSTLETHWAITE, ARNOLD, E.;KANG, ANDREW, H. |
分类号 |
A61K35/12;A61K38/39 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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