发明名称 |
Neutrokine-alpha fusion proteins |
摘要 |
The present invention relates to nucleic acid molecules encoding Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain. Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies or portions thereof that specifically bind Neutrokine-alpha and/or Neutrokine-alphaSV and diagnostic and therapeutic methods using these antibodies. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders using the compositions of the invention. |
申请公布号 |
US8212004(B2) |
申请公布日期 |
2012.07.03 |
申请号 |
US20050054539 |
申请日期 |
2005.02.10 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
YU GUO-LIANG;EBNER REINHARD;NI JIAN |
分类号 |
C07K14/475;A61K38/00;A61K38/16;A61K47/48;A61K49/00;C07K14/52;C07K14/705;C07K14/715;C07K16/24;C07K16/28;G01N33/564 |
主分类号 |
C07K14/475 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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