| 发明名称 |
SPIRO-OXINDOLE MDM2 ANTAGONISTS. |
| 摘要 |
<p>Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.</p> |
| 申请公布号 |
MX2012005507(A) |
申请公布日期 |
2012.07.03 |
| 申请号 |
MX20120005507 |
申请日期 |
2010.11.10 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN.* |
发明人 |
SHAOMENG WANG;SHANGHAI YU;WEI SUN;SANJEEV KUMAR;DUXIN SUN;PENG ZOU;YUJUN ZHAO;DONNA MCEACHERN |
| 分类号 |
C07D487/10;A61K31/407;A61P35/00;C07D491/107;C07D495/10 |
主分类号 |
C07D487/10 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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