发明名称 Dual-acting benzoimidazole antihypertensive agents
摘要 The invention relates to compounds having the formula: wherein Ar, r, n, X, R2, R2′, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and a process and intermediates for preparing such compounds.
申请公布号 US8212052(B2) 申请公布日期 2012.07.03
申请号 US20080330289 申请日期 2008.12.08
申请人 CHOI SEOK-KI;FATHEREE PAUL R.;MCKINNELL ROBERT MURRAY;OLSON BROOKE;THERAVANCE, INC. 发明人 CHOI SEOK-KI;FATHEREE PAUL R.;MCKINNELL ROBERT MURRAY;OLSON BROOKE
分类号 A61K31/4184;C07D235/08 主分类号 A61K31/4184
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