Porcint reproduktions- og respirations-syndrom-vaccine baseret på isolat JA-142
摘要
<p>Substantially avirulent forms of atypical porcine reproductive and respiratory syndrome (PRRS) virus and corresponding vaccines are provided which result from cell culture passaging of virulent forms of PRRS. The resultant avirulent atypical PRRS virus is useful as a vaccine in that PRRS specific antibody response is elicited by inoculation of host animals, thereby conferring effective immunity against both previously known strains of PRRS virus and newly isolated atypical PRRS virus strains. The preferred passaging technique ensures that the virus remains in a logarithmic growth phase substantially throughout the process, which minimizes the time required to achieve attenuation.</p>
申请公布号
DK2251419(T3)
申请公布日期
2012.07.02
申请号
DK20100169336T
申请日期
2000.04.21
申请人
UNITED STATES DEPARTMENT OF AGRICULTURE;BOEHRINGER INGELHEIM VETMEDICA, INC.
发明人
MENGELING, WILLIAM, L.;VORWALD, ANN;LAGER, KELLY;ROOF, MIKE;BURKHART, KELLY;GORCYCA, DAVID, E.