The invention provides a synthetic C. difficile PS-II cell wall saccharide. The invention also provides a process for purifying C. difficile PS-II saccharide from C. difficile bacterial cells resulting in reduced contamination. The saccharides may be used in vaccines, particularly as conjugates with carrier proteins.
申请公布号
CA2860331(A1)
申请公布日期
2012.06.28
申请号
CA20112860331
申请日期
2011.12.23
申请人
NOVARTIS AG
发明人
COSTANTINO, PAOLO;ADAMO, ROBERTO;ROMANO, MARIA ROSARIA;DANIEL, ELISA;BERTI, FRANCESCO;CAPPELLITTI, EMILIA;LAY, LUIGI
