AQUEOUS FORMULATIONS FOR COATING MICRONEEDLE ARRAYS
摘要
Aqueous formulations that include at least one active pharmaceutical ingredient; and at least one excipient, wherein the aqueous formulation has a viscosity of from 500 to 30,000 centipoise when measured at a shear rate of 100s-1 and a temperature of 25° C; a surface tension that is not greater than 60 dynes/cm when measured under ambient conditions; or a contact angle on a medical grade polymeric material of 50° or greater when measured under ambient conditions. Methods of coating and coated microneedle arrays using the aqueous formulations are also disclosed herein.
申请公布号
WO2011150144(A3)
申请公布日期
2012.06.28
申请号
WO2011US38029
申请日期
2011.05.26
申请人
3M INNOVATIVE PROPERTIES COMPANY;DETERMAN, AMY S.;JOHNSON, PETER R.;MOSEMAN, JOAN T.;WOLDT, RYAN T.;HANSEN, KRISTEN J.
发明人
DETERMAN, AMY S.;JOHNSON, PETER R.;MOSEMAN, JOAN T.;WOLDT, RYAN T.;HANSEN, KRISTEN J.