发明名称 Indole/Benzimidazole Compounds as mTOR Kinase Inhibitors
摘要 The present invention provides compounds that are kinase inhibitors, specifically PIK kinase inhibitors, more specifically, mTOR inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of kinases, specifically PIK kinase inhibitors, more specifically, mTOR such as cancer. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
申请公布号 US2012165334(A1) 申请公布日期 2012.06.28
申请号 US201013260715 申请日期 2010.02.10
申请人 BOEZIO ALESSANDRO;CHENG ALAN C.;COATS JAMES ROBERT;COPELAND KATRINA WOODIN;GRACEFFA RUSSELL;HARMANAGE JEAN-CHRISTOPHE;HUANG HONGBING;LA DANIEL;OLIVIERI PHILIP R.;PETERSON EMILY ANNE;SCHENKEL LAURIE;AMGEN INC. 发明人 BOEZIO ALESSANDRO;CHENG ALAN C.;COATS JAMES ROBERT;COPELAND KATRINA WOODIN;GRACEFFA RUSSELL;HARMANAGE JEAN-CHRISTOPHE;HUANG HONGBING;LA DANIEL;OLIVIERI PHILIP R.;PETERSON EMILY ANNE;SCHENKEL LAURIE
分类号 A61K31/53;A61K31/506;A61P35/00;C07D401/14;C07D403/04;C07D403/14 主分类号 A61K31/53
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