摘要 |
<P>PROBLEM TO BE SOLVED: To provide an HDL (high density lipoprotein) enhancer for producing a medicine for treating and/or preventing arteriosclerosis, in particular, coronary artery disease such as myocardial infarction and angina pectoris, hyperlipemia, diabetes, obesity, atherosclerosis, hyperglycemia and/or syndrome X. <P>SOLUTION: The compound is exemplified by formula. The HDL enhancer is completed by selecting a compound which can be made into a PPAR agonist, synthesizing many derivatives based on the structure of the selected compound, selecting a compound having high activity and desired pharmacological activity, and further performing the derivative synthesis thereof. <P>COPYRIGHT: (C)2012,JPO&INPIT |