发明名称 HDL ENHANCER
摘要 <P>PROBLEM TO BE SOLVED: To provide an HDL (high density lipoprotein) enhancer for producing a medicine for treating and/or preventing arteriosclerosis, in particular, coronary artery disease such as myocardial infarction and angina pectoris, hyperlipemia, diabetes, obesity, atherosclerosis, hyperglycemia and/or syndrome X. <P>SOLUTION: The compound is exemplified by formula. The HDL enhancer is completed by selecting a compound which can be made into a PPAR agonist, synthesizing many derivatives based on the structure of the selected compound, selecting a compound having high activity and desired pharmacological activity, and further performing the derivative synthesis thereof. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012121889(A) 申请公布日期 2012.06.28
申请号 JP20120007712 申请日期 2012.01.18
申请人 IYAKU BUNSHI SEKKEI KENKYUSHO:KK;SHIONOGI & CO LTD 发明人 ITAI AKIKO;MUTO SUSUMU;TOKUYAMA TATSUMITSU;FUKAZAWA HIROSHI;OHARA TAKAFUMI;KATO TERUKAZU
分类号 A61K31/428;A61K31/437;A61K31/454;A61K31/4545;A61K31/495;A61K31/496;A61K31/4995;A61K31/5377;A61K31/55;A61K31/551;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P43/00 主分类号 A61K31/428
代理机构 代理人
主权项
地址